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Now, my experience with gummies for anxiety has been a lot different than using gummies for pain. I’ve always had a positive effect with these edibles because CBD has an inherent trait of calming the nerves – in other words, alleviating stress. Migraine and CBD Oil | American Migraine Foundation For patients interested in CBD oil for the acute treatment of migraine, Dr. Silberstein says it is important to ensure that you are using a pure product. You are likely to receive a pure and safe product in states where CBD oil is legal and grown.